THE 9LIST TRAINING COURSES | MADHAVI GAVINI, DROPLETTE

HOW DROPLETTE'S MICRO INFUSING TECHNOLOGY HELPS YOU GET THE MOST OUT OF YOUR SKINCARE SUMMARY | HOW DROPLETTE'S MICRO INFUSING TECHNOLOGY HELPS YOU GET THE MOST OUT OF YOUR SKINCARE QUIZ

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MADHAVI GAVINI, Co-Founder

DROPLETTE

Madhavi Gavini and Rathi Srinivas have been fortunate enough to do impactful research in fields including drug discovery (a drug that Madhavi invented was granted the first FDA designation for pediatric heart disease since 1994), medical diagnostics (Rathi did her PhD in biomarkers & point of care diagnostics for resource-limited settings), and neuroscience. They’ve always dreamed of chasing the big problems in the world that can truly improve people’s lives.

Droplette was originally a project born on Madhavi’s kitchen table. They had just returned from a rare disease conference where they had learned about a debilitating skin disease called Epidermolysis Bullosa (EB). This rare genetic disease disproportionately affects pediatric patients and due to a single missing gene, the skin won't adhere to the muscle underneath. It causes immensely painful wounds and even a wound dressing or an ointment is extremely painful.

They asked themselves: what if they could just deliver the missing gene or even drugs like pain relievers or antibiotics into the skin of these patients with no pain? They bought some electronic components from Ebay and got to work. They did some experiments using the prototypes that they had built at home and found that they had stumbled upon some really fascinating fluid physics phenomena that could actually significantly enhance delivery of drugs across the skin. They filed their first patent and started looking for funding: their first-ever grant funding into Droplette actually came from NASA; the fluid physics excited them too.

Although they started out working on the Droplette technology as a painless, needle-free delivery solution that could hopefully one-day cure EB, they quickly realized that their technology has applications in every realm of skincare. Both of them had their share of skincare issues: between them they’ve dealt with acne in their twenties, hyperpigmentation, dry skin, and scarring and they’ve tried every over-the-counter product out there. As it turns out, most of them don’t really work or offer a holistic solution.

They wanted to use the Droplette technology to effectively deliver tried and true ingredients into the skin and expand the use of their technology to consumers. This isn’t to say that they abandoned their original mission: they are supported by the NIH in continuing the EB research and are currently partnered with Walter Reed Army Institute to use Droplette to treat blast wounds that impact soldiers in the field.

They’ve worked on engineering & optimizing this technology for many years and along the way, they’ve spoken with countless physicians, drug delivery experts, and end users. The device itself has gone through dozens of iterations so that they could get the form factor, the feel, and the efficacy perfectly right. Alongside the device, they’ve developed their formulations to only include those essential ingredients that are necessary for your skin, and have spent years in the lab tweaking the ingredients and concentrations to achieve the best results.

More recently, they’ve built an amazing team and are fortunate to work with some of the world’s best advisors and experts, including Dr. Leonard Miller, Dr. Rox Anderson, and Dr. Samir Mitragotri. They believe that they have successfully tackled the two biggest challenges in skincare with their technology: pain and effective delivery. They have created this as a medical-grade product and are so excited to finally bring Droplette into the hands of users like you.